www.plastid.no © 2007                    

Research

Professor Simon Geir Møller has been an independent investigator and research group leader since 2001 (at the University of Leicester, UK) with over 15 years personal research experience in plastid biology and plastid genetic engineering. At the University of Stavanger and Centre for Organelle Research (CORE) Professor Møller and his laboratory have extensive expertise in plastid biology with emphasis on plastid transformation, Fe-S cluster biogenesis and plastid division. The group has attracted research funding of over 19MNOK from NRC, BBSRC, UFD, The Leverhulme Trust and EMBO; 6.2MNOK of which towards the Plastid AS project.

Since setting up Plastid AS, the team are continuing research into plastid transfomation technologies and applications. Current research projects include Norwegian Research Council and own funding within the FUGE (functional genomics) programme in fsh vaccines and crop research. A key focus area is the production of previously impossible malaria proteins for screening programmes.

The plastid research project has verified that the technology functions as expected and has produced and purified several proteins, including proteins that have proved impossible to produce using traditional production systems:

• ATPase
• Biomarker protein
• Malaria proteins
• Antibodies
• Restriction Enzymes
    Polymerases
    Ligases
    Kinases
    Phosphatases
    Integrase

Selected Publications: Jodi Maple and Simon Geir Møller (2007). Interdependency of Min complex formation and localization controls symmetric plastid division. J Cell Science. 120, 3446-3456. Astrid E Tveitaskog, Jodi Maple and Simon Geir Møller (2007). Plastid division in an evolutionary context. Biol. Chem., 388, 937-942. Jodi Maple and Simon Geir Møller (2007). Plastid division coordination across a  double-membraned structure. FEBS Letters581, 2162-2167 Jodi Maple, Lea Vojta, Jurgen Soll and Simon Geir Møller (2007) ARC3 is a stromal Z-ring accessory protein essential for plastid division.EMBO Rep. 8, 293-299. Jodi Maple and Simon Geir Møller (2006). Plastid Division: Evolution, Mechanism and Complexity. Annals Bot.99, 565-579. Xiang Ming Xu and Simon Geir Møller (2006) AtSufE is an essential activator of plastidic and mitochondrial desulfurases in Arabidopsis. EMBO J. 25. 900-909. Jodi Maple, Cassie Aldridge and Simon Geir Møller (2005) Plastid division is mediated by combinatorial assembly of plastid division proteins. Plant J. 43. 811-823 Jodi Maple, Cassie Aldridge and Simon Geir Møller (2005) The molecular biology of plastid division. J. Ex. Bot.56, 1061-1077. Xiang Ming Xu, Sally Adams, Nam-Hai Chua and Simon Geir Møller (2005) AtNAP1 represents an atypical SufB protein in Arabidopsis plastids. J. Biol. Chem. 280, 6648-6654. Xiang Ming Xu and Simon Geir Møller (2004) AtNAP7 is a plastidic SufC-like ABC/ATPase essential for Arabidopsis embryogenesis. Proc.Natl.Acad.Sci.U.S.A. 101, 9143-9148. Jodi Maple, Makoto T. Fujiwara, Nobutaka Kitahata, Tracey Lawson, Neil Baker, Shigeo Yoshida and Simon Geir Møller (2004)GIANT CHLOROPLAST 1 is essential for correct plastid division in Arabidopsis. Current Biology. 14, 776-781.

FUGE Research programme -
Oral Vaccines in Salmonids

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1,5 millioner til Simon G Møller fra Forskningsrådet

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